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HelpTest ID: ADULT Adulterants Survey, Random, Urine
Useful For
Assessment of possible adulteration of a urine specimen submitted for drug of abuse testing
Providing the creatinine concentration for normalization purposes
Testing Algorithm
For more information see Adulterant Survey Algorithm.
Special Instructions
Reporting Name
Adulterants Survey, USpecimen Type
UrineOrdering Guidance
For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody information, see ADLTX / Adulterants Survey, Chain of Custody, Random, Urine.
Specimen Required
Container/Tube: Plastic, 60-mL urine bottle
Specimen Volume: 1.5 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Additional Information: Submitting less than 1.5 mL may compromise the ability to perform all necessary testing.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days | ||
| Ambient | 72 hours |
Clinical Information
Specimen adulteration is the manipulation of a sample that may cause false-negative test results for the presence of drugs of abuse. Common adulterants that may affect testing are water, soap, bleach, vinegar, oxidants, and salt. The adulteration testing includes assessment of creatinine concentration, pH, urine specific gravity, presence or absence of an oxidant, and presence or absence of nitrite.
Interpretation
For information see Adulterant Survey Algorithm.
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 to 2 daysLOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ADULT | Adulterants Survey, U | 58714-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 20606 | Creatinine, U | 2161-8 |
| 22312 | Specific Gravity | 5810-7 |
| 23509 | pH | 2756-5 |
| 23511 | Oxidants | 58714-7 |
| 23510 | Nitrites | 32710-6 |
| 30914 | Comment | 48767-8 |
Method Name
Spectrophotometry (SP)
Reference Values
Cutoff concentrations
Oxidants: 200 mg/L
Nitrites: 500 mg/L
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
Clinical Reference
1. US Department of Health and Human Services, Substance Abuse and Mental Health Services Administration (SAMHSA). Mandatory Guidelines for Federal Workplace Drug Testing Programs. Federal Register. 2017 January 23;82(13):FR 7920. Accessed July 15, 2024. Available at www.samhsa.gov/sites/default/files/workplace/frn_vol_82_7920_.pdf
2. US Department of Health and Human Services, Substance Abuse and Mental Health Services Administration (SAMHSA). Drug-Free Workplace Programs: Employer Resources. Updated October 11, 2023. Accessed July 15, 2024. Available at www.samhsa.gov/workplace/resources
3. US Department of Health and Human Services (HHS), Substance Abuse and Mental Health Services Administration (SAMHSA). Mandatory Guidelines for Federal Workplace Drug Testing Programs. Updated October 12, 2023. Accessed July 15, 2024. Available at www.federalregister.gov/documents/2023/10/12/2023-21734/mandatory-guidelines-for-federal-workplace-drug-testing-programs
mml-adulterants, mml-substancemonitoring