Sign in →

Test ID: ADULT Adulterants Survey, Random, Urine

Useful For

Assess the possible adulteration of a urine specimen submitted for drug of abuse testing, as well as for providing the urine creatinine for "creatinine normalization"

Testing Algorithm

See Adulterant Survey Algorithm in Special Instructions.

Special Instructions

Reporting Name

Adulterants Survey, U

Specimen Type


Specimen Required

Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 20 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody information, see ADLTX / Adulterants Survey, Chain of Custody, Urine.

2. Submitting less than 20 mL will compromise our ability to perform all necessary testing.

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Clinical Information

Specimen adulteration is the manipulation of a sample that may cause falsely negative test results for the presence of drugs of abuse. Common adulterants that may affect testing are water, soap, bleach, vinegar, oxidants, and salt. The adulteration testing includes assessment of creatinine concentration, pH, urine specific gravity, presence or absence of an oxidant, and presence or absence of nitrite.


See Adulterant Survey Algorithm in Special Instructions.

Day(s) and Time(s) Performed

Monday through Saturday

Analytic Time

Same day/1 day

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
ADULT Adulterants Survey, U 58714-7


Result ID Test Result Name Result LOINC Value
20606 Creatinine, U 2161-8
22312 Specific Gravity 5810-7
23509 pH 2756-5
23511 Oxidants 58714-7
23510 Nitrites 2657-5
30914 Comment 48767-8

Method Name

Spectrophotometry (SP)

Reference Values

Cutoff concentrations

Oxidants: 200 mg/L

Nitrites: 500 mg/L

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.


If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen. 

Mayo Clinic Laboratories | Therapeutics Catalog Additional Information:

mml-adulterants, mml-substancemonitoring